Zestoretic Side Effects

There are many possible side effects associated with Zestoretic. Side effects that are most commonly reported with the medication include dizziness, headache, fatigue, and cough. Some rare but possible side effects of Zestoretic include dry mouth, constipation, and heartburn. When side effects do occur with Zestoretic, they tend to be minor; however, if you experience serious problems such as seizures or unexplained swelling of the head or neck, notify your healthcare provider immediately.

 

Zestoretic Side Effects: An Overview

As with any medicine, there are possible side effects with Zestoretic® (lisinopril-hydrochlorothiazide). However, not everyone who takes the medicine will experience side effects. If Zestoretic side effects do occur, they are generally mild and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
(The side effects discussed below are not a complete list of side effects reported with Zestoretic. Your healthcare provider can discuss a more complete list of Zestoretic side effects with you.)
 

Common Zestoretic Side Effects

Zestoretic has been studied extensively in clinical trials for people with
 high blood pressure. Before medicines are approved, they must go through several clinical studies where many people are given a particular medicine and are then compared to a group of people not given the medicine. In these studies, the side effects are always documented. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. In these studies, the most common Zestoretic side effects included:
 
  • Dizziness -- reported in up to 7.5 percent of people
  • Headache -- reported in up to 5.2 percent of people
  • Cough -- reported in up to 3.9 percent of people
  • Fatigue -- reported in up to 3.7 percent of people
  • Dizziness, lightheadedness, or fainting when standing from a sitting or lying down position (known medically as orthostatic effects) -- reported in up to 3.2 percent of people.
     
Other side effects of Zestoretic occurring in more than 1 percent of people include, but are not limited to:
 
(Zestoretic Side Effects Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;