(Click Valturna Uses for more information on what this medication is used for, including possible off-label indications.)
Valturna is made by Novartis Pharmaceuticals Corporation.
Valturna contains two different medications that work in different ways.
Both medicines target the renin angiotensin aldosterone system (RAAS), but they work at different points in the process. The RAAS is an important regulator of
blood pressure in the body.
Aliskiren is classified as a renin inhibitor. It is the first medication of its kind. Renin is an enzyme produced in the kidneys that acts throughout the body. It works to convert angiotensinogen to angiotensin I.
A different enzyme (angiotensin-converting enzyme, or ACE) then converts angiotensin I to angiotensin II, a powerful substance that increases blood pressure by narrowing blood vessels and indirectly stimulating the kidneys to retain salt.
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. By blocking angiotensin II, this drug helps to relax the blood vessels, thereby
lowering blood pressure.
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