Valturna contains two different medications that work in different ways. Both medicines target the renin angiotensin aldosterone system (RAAS), but they work at different points in the process. The RAAS is an important regulator of
blood pressure in the body.
Aliskiren is classified as a renin inhibitor. It is the first medication of its kind. Renin is an enzyme produced in the kidneys that acts throughout the body. It works to convert angiotensinogen to angiotensin I.
A different enzyme (angiotensin-converting enzyme, or ACE) then converts angiotensin I to angiotensin II, a powerful substance that increases blood pressure by narrowing blood vessels and indirectly stimulating the kidneys to retain salt.
Valsartan belongs to a class of drugs called angiotensin II receptor blockers. By blocking angiotensin II, it helps to relax the blood vessels, thereby
lowering blood pressure.
Valturna Use in Children or Teens
Valturna is not approved for children or teens. Talk with your child's healthcare provider about the benefits and risks of using Valturna in these age groups.
Off-Label Uses for Valturna
On occasion, your healthcare provider may recommend this drug for something other than
high blood pressure. At this time, there are no universally accepted
off-label Valturna uses.
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