Uniretic Overdose

It is possible to overdose on Uniretic (moexipril/HCTZ). Common symptoms that may occur with taking too much of this drug may include extremely low blood pressure, an electrolyte imbalance, and dehydration. Treatment options can include "pumping the stomach," administering activated charcoal, and providing supportive care. If you believe you have taken an overdose, seek immediate medical attention.

Can You Take Too Much Uniretic?

Uniretic® (moexipril/HCTZ) is a combination prescription medication approved to treat hypertension (high blood pressure). It contains moexipril, an angiotensin-converting enzyme inhibitor (ACE inhibitor), and hydrochlorothiazide (HCTZ), a diuretic or "water pill."
 
As with most medications, it is possible to take too much Uniretic. The specific effects of an overdose can vary, depending on a number of factors, including the Uniretic dosage and whether it was taken with any other medications or substances.
 

Effects of an Overdose

People who take a Uniretic overdose may experience the following symptoms:
 
  • Extremely low blood pressure (hypotension)
  • Dehydration
  • Dizziness, lightheadedness, or fainting
  • A slow or irregular heart rate
  • Electrolyte problems, including low blood levels of potassium, sodium, or chloride, which may cause the following symptoms:
 
    • Dry mouth
    • Thirst
    • Weakness
    • Tiredness
    • Restlessness
    • Confusion
    • Muscle pains or cramps
    • Nausea and vomiting
    • Seizures
    • Decrease in urination.
 

Treating a Uniretic Overdose

If the overdose was recent, a healthcare provider may administer activated charcoal or "pump the stomach" to help reduce the amount of the medication that is absorbed into the bloodstream.
 
In addition, treatment may involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive care for a Uniretic overdose may include:
 
  • Medications to increase blood pressure
  • Fluids through an intravenous (IV) line
  • Close monitoring of the kidneys and heart
  • Close monitoring of blood electrolyte levels.
 
It is unknown if kidney dialysis is helpful in removing Uniretic from the body.
 
It is important that you seek medical attention immediately if you believe that you or someone else may have overdosed on this medication.
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