Twynsta Side Effects

Possible reactions to Twynsta include headaches, swelling, and fatigue. In most cases, people can take this medication without any problems. However, contact your healthcare provider if you develop serious side effects while taking Twynsta, such as chest pain, decreased urine production, or difficulty breathing. Even if the reaction is unrelated to the medication, your healthcare provider can help diagnose and treat the problem.

An Introduction to Twynsta Side Effects

Just like any medicine, Twynsta® (telmisartan/amlodipine) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Twynsta. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Twynsta

Twynsta has been studied extensively in clinical trials. In these studies, one group of people received Twynsta, while another group was given a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
Twynsta contains a combination of two medications: telmisartan (Micardis®) and amlodipine (Norvasc®). These two components have been studied individually in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to those that occurred in a group of people taking a placebo.
In clinical studies, the most common side effects of Twynsta or the individual components of it included:
  • Swelling (edema) in the hands, ankles, or feet -- in up to 11.3 percent of people
  • Headaches -- up to 7.3 percent
  • Infection of the sinuses or upper respiratory tract -- up to 7.0 percent
  • Feelings of a rapidly or forcefully beating heart (heart palpitations) -- up to 4.5 percent
  • Fatigue, or feeling tired or sleepy -- up to 4.5 percent
  • Dizziness -- up to 3.4 percent
  • Back pain - up to 3.0 percent
  • Diarrhea -- up to 3.0 percent
  • Nausea -- up to 2.9 percent
  • Flushing (a sudden redness and warmth of the face and neck) -- up to 2.6 percent.
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Twynsta Medication Information

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