Twynsta and Pregnancy
The U.S. Food and Drug Administration classifies Twynsta (telmisartan/amlodipine) as a pregnancy Category D medication. This means that it may not be safe for pregnant women to use this medication. Some animal studies indicated that the drug might cause several problems, such as miscarriages and birth defects.
Can I Take Twynsta When Pregnant?
Twynsta® (telmisartan/amlodipine) is a prescription medication used to treat high blood pressure, known medically as hypertension. It contains two drugs -- telmisartan (Micardis®) and amlodipine (Norvasc®).
Twynsta may cause harm to an unborn child, based on the results of animal studies and problems reported when pregnant women took medications like telmisartan, one of the components of Twynsta.
What Is Pregnancy Category D?
The FDA uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but appear to cause harm to the fetus in animal studies.
Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents. Thus, a pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child.