Uses of Toprol-XL most commonly involve the treatment of conditions related to the heart and blood vessels, including high blood pressure and congestive heart failure. The medication is also used to treat symptoms of angina. "Off-label" Toprol-XL uses may include the treatment of conditions such as hyperthyroidism. Toprol-XL is not approved for use in children; however, it is sometimes used off-label to treat children with certain conditions.
In clinical studies, Toprol-XL has been shown to significantly lower systolic and diastolic blood pressure. The higher the dose of Toprol-XL, the greater the drop in blood pressure is expected to be. By lowering blood pressure, Toprol-XL can decrease the risks that occur with long-term high blood pressure (see Effects of High Blood Pressure). Toprol-XL does not, however, cure high blood pressure.