Who Makes Tekturna?
It is made by Novartis Pharmaceuticals Corporation.
How Does It Work?
Tekturna is classified as a renin inhibitor. It is the first medication of its kind. Renin is an enzyme produced in the kidneys that acts throughout the body. It works to convert angiotensinogen to angiotensin I. A different enzyme (angiotensin-converting enzyme, or ACE) then converts angiotensin I to angiotensin II, a powerful substance that increases blood pressure
by narrowing blood vessels and indirectly stimulating the kidneys to retain salt.
Various blood pressure medications
work during different steps in this process (such as ACE inhibitors or angiotensin II receptor blockers, known as ARBs). However, Tekturna is different; it acts at the beginning of the process, preventing renin from converting angiotensinogen to angiotensin I (the first step in the process).