Tarka Uses (Cont.)

How Does Tarka Work?

Tarka is a combination of two medicines -- trandolapril (sold under the brand Mavik®) and verapamil ER (sold under several brands and as a generic). Mavik is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short. Mavik helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Mavik causes blood vessels to relax.
 
Verapamil ER is part of a class of drugs called calcium channel blockers. It is a slow release version of verapamil (the ER stands for extended-release). Verapamil ER helps to slow down the rate at which calcium moves into the walls of your blood vessels. This, in turn, helps to relax the vessels, causing a decrease in blood pressure. It also makes it easier for the heart to pump blood.
 
Because of the effects of both Mavik and verapamil ER, Tarka causes a greater drop in blood pressure than when either medicine is used alone.
 

Is Tarka Used in Children?

Tarka has not been approved for use in children.
 

Off-Label Tarka Uses

On occasion, a healthcare provider may recommend Tarka for treating a condition other than those listed above. This is called an "off-label" use. At this time, there are no universally accepted off-label Tarka uses.

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;