Tarka is a combination of two medicines --
trandolapril (sold under the brand
Mavik®) and
verapamil ER (sold under several brands and as a generic). Mavik is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short. Mavik helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Mavik causes blood vessels to relax.
Verapamil ER is part of a class of drugs called
calcium channel blockers. It is a slow release version of verapamil (the ER stands for extended-release). Verapamil ER helps to slow down the rate at which calcium moves into the walls of your blood vessels. This, in turn, helps to relax the vessels, causing a decrease in
blood pressure. It also makes it easier for the heart to pump blood.
Because of the effects of both Mavik and verapamil ER, Tarka causes a greater drop in blood pressure than when either medicine is used alone.
Is Tarka Used in Children?
Tarka has not been approved for use in children.
On occasion, a healthcare provider may recommend Tarka for treating a condition other than those listed above. This is called an "
off-label" use. At this time, there are no universally accepted off-label Tarka uses.