Tarka Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Tarka is combined with any of the drugs listed above.
Anesthetics
If you will be receiving anesthesia (such as for surgery) make sure your anesthesiologist knows that you are taking Tarka, as this may influence the choice and dosage of anesthetics.
Beta Blockers
If you are taking Tarka and a
beta blocker, your
blood pressure or heart rate may decrease too much. Your healthcare provider may choose to monitor your progress closely.
Carbamazepine
Tarka may increase the level of
carbamazepine in the blood, possibly increasing the risk of
carbamazepine side effects. Check with your healthcare provider before taking these medications together.
Certain Arrhythmia Medications
If you are taking Tarka with certain arrhythmia medications, your blood pressure or heart rate may decrease too much. Irregular heart rhythms may occur. Check with your healthcare provider before combining Tarka with an arrhythmia medication.
Certain Statin Medications
Tarka may increase the level of some
statins in the blood, increasing the risk of muscle problems or other
statin side effects. When combined with Tarka, the maximum daily dosage of
simvastatin is 10 mg, and the maximum daily dosage of
lovastatin is 40 mg. Lower-than-normal dosages of
atorvastatin may be recommended as well.
Clarithromycin
There have been reports of low blood pressure, slow heart rate, and lactic acidosis (a dangerous condition) when Tarka was combined with
clarithromycin. Check with your healthcare provider before taking these medications together.