Quinaretic

Quinaretic is a prescription drug licensed to treat high blood pressure (hypertension) in adults. It consists of two medications: a diuretic and an ACE inhibitor. Quinaretic can significantly lower blood pressure levels by causing blood vessels to relax and causing a decrease in blood volume. Potential side effects of Quinaretic may include headache, cough, dizziness, and fatigue.

 

What Is Quinaretic?

Quinaretic™ (quinapril HCL-hydrochlorothiazide) is a prescription medicine used for controlling high blood pressure (hypertension) in adults; however, it is not a cure for high blood pressure.
 
Quinaretic has not been approved for use in children.
 
(Click What Is Quinaretic Used For? for more information on Quinaretic uses.)
 

Who Makes Quinaretic?

Quinaretic is manufactured by Amide Pharmaceutical.
 

How Does Quinaretic Work?

Quinaretic is a combination of two medicines --
 Accupril® (quinapril hydrochloride) and hydrochlorothiazide. Accupril is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short. Accupril helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Accupril causes blood vessels to relax.
 
Hydrochlorothiazide (HCT for short) is a diuretic (a type of drug commonly referred to as a "water pill"). It works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, hydrochlorothiazide causes a decrease in blood volume.
 
Because of the effect of both Accupril and hydrochlorothiazide, Quinaretic can lower blood pressure. As a result of its combined effects, Quinaretic causes a greater drop in blood pressure than when either medicine is used alone.
 
(Quinaretic Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;