Drug Interactions With Propranolol XL

Propranolol XL Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when propranolol XL is combined with any of the drugs listed above.
 
ACE Inhibitors
Combining propranolol XL with an ACE inhibitor may increase the risk of dangerously low blood pressure or breathing problems. Check with your healthcare provider before taking such medications together.
 
Alcohol
Alcohol might increase or decrease the level of propranolol XL in your blood unpredictably. Check with your healthcare provider before drinking alcohol while taking propranolol XL. Short-term use of alcohol may increase propranolol XL levels in the bloodstream, while long-term alcohol use may actually decrease levels of the drug.
 
Alpha Blockers
Combining propranolol XL with an alpha blocker can increase the risk of dangerously low blood pressure (hypotension). Check with your healthcare provider before combining such medications.
 
Calcium Channel Blockers
Combining propranolol XL with certain calcium channel blockers may cause dangerously low blood pressure and (for verapamil or diltiazem) a slow heart rate (bradycardia) or heart failure. You may need to be monitored very closely if you take these medications together. In some cases, it is not recommended to combine propranolol XL with a calcium channel blocker.
 
Certain Arrhythmia Medications
Combining propranolol XL with certain arrhythmia medications may cause a dangerously slow heart rate (bradycardia). You may need to be monitored very closely if you take these medications together. In some cases, it is not recommended to combine propranolol XL with an arrhythmia medication.
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Propranolol XL Drug Information

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