Prinzide Drug Interactions

Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both Prinzide and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
 
Gold
If you are on liquid gold therapy, there is a possibility that Prinzide will interact with the liquid gold. Symptoms of such an interaction may include facial flushing, nausea, vomiting, and low blood pressure. Contact your healthcare provider if you experience any of these symptoms.
 
Insulin
Taking insulin with Prinzide may cause high blood sugar (hyperglycemia). In your particular situation, your healthcare provider may monitor you more closely and adjust your dose of insulin as needed.
 
Oral Diabetes Medication
Taking an oral diabetes medication with Prinzide may increase blood sugar levels. If you are taking oral diabetes medications with Prinzide, your healthcare provider may monitor you more closely and adjust your dose of diabetes medications as needed.
 
Other Blood Pressure Medicine
When taking Prinzide with another high blood pressure medication, your blood pressure may decrease too much. In order to decrease the chances of developing this Prinzide interaction, your healthcare provider may monitor you more closely and/or change the dose of either medicine.
 
Alcohol
When taking Prinzide with alcohol, your blood pressure may decrease too much. Be sure to talk with your healthcare provider about drinking alcohol while taking Prinzide.
 
Barbiturates (Amytal, Butisol Sodium, Luminal, Mysoline, Nembutal, Pentothal)
When taking Prinzide with a barbiturate, your blood pressure may decrease too much. In order to decrease the chances of developing this Prinzide interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of Prinzide, and monitor you more closely.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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