Prinzide Drug Interactions (Cont.)

More Detail on Prinzide Interactions

 
Diuretics (Demadex, Lasix)
When taking Prinzide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when you first start taking Prinzide. In order to decrease your chances of experiencing such an interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of Prinzide, and monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and Prinzide may add to the damage that your kidneys are already suffering. Also, NSAIDs may decrease the blood pressure-lowering effects of Prinzide. Talk to your healthcare provider about using NSAIDs and Prinzide together in your situation.
 
Potassium Supplements or Salt Substitutes With Potassium
If you are taking Prinzide with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. Talk to your healthcare provider about using potassium and Prinzide together in your situation.
 
Potassium-Sparing Diuretics (Aldactone, Dyrenium, Midamor)
If you are taking both Prinzide and a potassium-sparing diuretic, your body may metabolize them differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely.
 
Lithium (Eskalith, Lithane, Lithonate, Lithotabs)
If you are taking both Prinzide and lithium, your body may metabolize the drugs differently than intended and increase the lithium levels in the blood. Your healthcare provider may choose to monitor your serum lithium levels more frequently.
(Prinzide Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;