Prinzide Drug Interactions

More Detail on Prinzide Interactions

The following sections explain some of the potential negative interactions that may occur when certain drugs are combined with Prinzide.
 
Aliskiren
Combining Prinzide with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
 
Prinzide should never be combined with aliskiren in people with diabetes, who may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.
  
Angiotensin II Receptor Blockers (ARBs)
Combining Prinzide with an ARB may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required. 
 
Diuretics (Demadex, Lasix)
When taking Prinzide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when you first start taking Prinzide. In order to decrease your chances of experiencing such an interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of Prinzide, and monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
If you have kidney disease or kidney failure, taking both NSAIDs and Prinzide may add to the damage that your kidneys are already suffering. Also, NSAIDs may decrease the blood pressure-lowering effects of Prinzide. Talk to your healthcare provider about using NSAIDs and Prinzide together in your situation.
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Prinzide Drug Info

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