Norvasc and Pregnancy

In animal studies of Norvasc and pregnancy, the drug was shown to cause certain problems in rabbits and rats. However, animals do not always respond to medicines the same way that humans do, and a healthcare provider can still prescribe the drug if the benefits outweigh the risks. If you are taking Norvasc and pregnancy occurs, let your healthcare provider know.

An Overview of Norvasc and Pregnancy

For people who are pregnant, Norvasc® (amlodipine besylate) may not be safe. This is based on animal studies that looked at the effects of Norvasc during pregnancy.

Norvasc and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Norvasc was given a pregnancy Category C rating because of potential problems in animal studies. When given to pregnant rabbits and rats, Norvasc caused increased miscarriages. Norvasc also caused labor to be longer in rats. Norvasc did not cause any birth defects in animal studies.
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.

Norvasc and Pregnancy: Summary

If you are pregnant or thinking of becoming pregnant while taking Norvasc, let your healthcare provider know. Your healthcare provider will consider both the benefits and risks of Norvasc during pregnancy before making a recommendation for your particular situation.
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