Nifedipine Drug Interactions

If miconazole, warfarin, or certain other medications are taken with nifedipine, drug interactions can occur. These interactions can result in problems such as increased or decreased drug levels in the blood and increased risk of side effects (such as low blood pressure). To reduce your risk of nifedipine drug interactions, talk to your healthcare provider about the specific interactions that may apply to you.

 

An Overview of Nifedipine Drug Interactions

 Nifedipine can potentially interact with a number of other medicines. Some of the medicines that may lead to nifedipine drug interactions include:
 
  • Certain antibiotics or antifungals, such as:
o Erythromycin (Ery-Tab®)
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Neoral®)
o Miconazole
o Quinupristin and dalfopristin (Synercid®)
o Telithromycin (Ketek®)
  • Beta blockers, such as:
o Bisoprolol (Zebeta®)
o Nadolol (Corgard®)
o Sotalol (Betapace®)
o Timolol (Blocadren®)
 
  • Digoxin (Digitek®, Lanoxin®)
 
  • Grapefruit juice
 
  • Quinidine
 
 
  • Protease inhibitors, such as:
  • Rifamycin derivatives, such as rifabutin (Mycobutin®), rifampin (Rifadin®), or rifapentine (Priftin®).
 
 
 
  • Tacrolimus (Prograf®)
 
  • Warfarin (Coumadin®, Jantoven®).
     
(Nifedipine Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;