Nifedipine Drug Interactions

Nefazodone
Nefazodone can increase the level of nifedipine in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to decrease your nifedipine dose to prevent this drug interaction from occurring.
 
Protease Inhibitors
Protease inhibitors can increase the level of nifedipine in your blood, which may increase your risk of side effects. Your healthcare provider may need to decrease your nifedipine dose to prevent this from occurring.
 
Quinidine
Nifedipine can decrease the level of quinidine in your blood, perhaps making it less effective. Also, quinidine may increase the level of nifedipine in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications to prevent interactions from occurring.
 
Rifamycin Derivatives
Rifamycin derivatives can greatly reduce the level of nifedipine in your blood, perhaps making it much less effective. People are typically advised not to combine nifedipine with rifamycin derivatives. In particular, rifampin and nifedipine should never be taken together.
 
Certain Seizure Medications
Taking nifedipine with certain seizure medications can decrease the level of nifedipine in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of nifedipine to prevent this drug interaction from occurring.
 
St. John's Wort
St. John's wort can decrease the level of nifedipine in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of nifedipine if you are taking St. John's wort.
 
Tacrolimus
Nifedipine can increase the level of tacrolimus in your blood, possibly increasing your risk of side effects. Your healthcare provider should monitor the level of tacrolimus in your blood and may need to decrease your tacrolimus dosage to prevent drug interactions from occurring.
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Nifedipine Drug Information

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