Maxzide Drug Interactions

Maxzide may be less effective in people who overuse laxatives or who use laxatives chronically. Ask your healthcare provider about using laxatives while taking Maxzide.
Taking Maxzide with lithium may increase the level of lithium in your blood, potentially increasing your chances of side effects. It is generally not recommended that you take lithium with diuretics, including Maxzide. Depending on your situation, your healthcare provider may need to monitor your lithium level more closely or change your lithium dose.
Nonsteroidal Anti-Inflammatory Drugs
Combining Maxzide with nonsteroidal anti-inflammatory drugs (NSAIDs) can make Maxzide less effective and may increase your risk of Maxzide side effects. If you are taking these drugs together, your healthcare provider may need to increase your dose of Maxzide or may suggest an alternative to NSAIDs.
Taking methenamine with Maxzide may make methenamine less effective. Talk with your healthcare provider about taking these medications together.
Potassium-Containing Products
In general, products containing potassium should not be used with Maxzide due to the risk of high potassium levels (hyperkalemia).
Maxzide should not be taken with spironolactone. Taking these two medications together increases your risk of high potassium levels (hyperkalemia).
Your healthcare provider may need to adjust your warfarin dose when you are starting or stopping Maxzide.

Final Thoughts on Maxzide Drug Interactions

It is possible that not all Maxzide drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
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