Toprol-XL works by blocking beta receptors, which causes the reverse effect of stress hormones. As a result, Toprol-XL produces effects that help decrease heart rate and both systolic and diastolic blood pressure. The medication also decreases the workload of the heart, which increases the efficiency of the heart and allows more blood to be pumped out to the rest of the body.
By decreasing the workload of the heart, the medication can also decrease the number of angina attacks and increase exercise tolerance. For people with congestive heart failure, the effects of Toprol-XL on the heart and blood vessels have been shown to result in a decrease in hospitalizations and loss of life from congestive heart failure.
(Click Toprol-XL for a more in-depth look at Toprol-XL and its effects, including information on how it works, general dosing guidelines, and what to know before starting treatment with this medication.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Toprol-XL [package insert]. Wilmington, DE: AstraZeneca LP;2007 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed January 9, 2009.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed January 9, 2008.
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