Blood Pressure Home > What Is Quinaretic Used For?
Quinaretic is a combination of two medicines -- Accupril® (quinapril) and hydrochlorothiazide. Accupril is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short. Accupril helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Accupril causes blood vessels to relax.
Hydrochlorothiazide is a diuretic (a type of drug commonly referred to as a "water pill"). It works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, hydrochlorothiazide causes a decrease in blood volume.
Because of the effect of both Accupril and hydrochlorothiazide, Quinaretic can lower blood pressure. As a result of its combined effects, Quinaretic causes a greater drop in blood pressure than when either medicine is used alone.
Quinaretic has not been approved for use in children.
On occasion, your healthcare provider may recommend Quinaretic for treating a condition other than hypertension. This is called an "off-label" use. At this time, there are no universally accepted off-label Quinaretic uses.