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Micardis Drug Interactions ExplainedThe following sections explain in detail the potentially negative interactions that can occur when Micardis is combined with any of the drugs listed above.
Combining Micardis with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required. Aliskiren and Micardis should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate to severe kidney problems.
Combining Micardis with an ACE inhibitor could negatively affect your kidney function. If you must take Micardis along with an ACE inhibitor, your healthcare provider should monitor your kidney function (using a simple blood test) regularly.
One ACE inhibitor in particular (ramipril) is specifically not recommended for use in combination with Micardis. Ramipril may decrease the level of Micardis in the blood, and Micardis may increase the level of ramipril in the blood.
Digoxin (Digitek, Lanoxicaps, Lanoxin)