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There are a number of potential side effects with Lotrel; however, depression does not appear to be one of them. Based on extensive clinical studies, depression was not reported as either a common or rare side effect. Depression is extremely common in society today. Therefore, if you notice any symptoms of depression while taking Lotrel, it's important to talk to your healthcare provider.
Does Lotrel Cause Depression?There are several possible side effects for people taking Lotrel® (benazepril hydrochloride and amlodipine). Depression, however, does not appear to be one of them. This data comes from clinical trials where Lotrel was extensively studied and its side effects were documented.
Before medicines are approved, they must go through several clinical studies in which thousands of people are given a particular medicine and are then compared to a group of people who did not receive the medicine. In these studies, side effects are always documented.
As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. Side effects are then usually separated into those side effects that occur in more than 1 percent of people and those that occur in less than 1 percent of people.
For people taking Lotrel, depression was not reported as either a common or rare side effect.
Lotrel and Depression: What to Look ForWhile depression may not be a reported side effect of Lotrel, it is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) has depression. Therefore, knowing the symptoms of depression can be helpful.
Possible depression symptoms may include:
- Persistent sad, anxious, or "empty" mood
- Feelings of hopelessness and pessimism
- Feelings of guilt, worthlessness, and helplessness
- Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
- Decreased energy; fatigue; feeling "slowed down"
- Difficulty concentrating, remembering, and making decisions
- Insomnia, early-morning awakening, or oversleeping
- Appetite and/or weight loss, or overeating and weight gain
- Thoughts of death or suicide; suicide attempts
- Restlessness and irritability
- Persistent physical symptoms, such as headaches, digestive disorders, and chronic pain, that do not respond to treatment.
Keep in mind that there are other conditions that can share similar symptoms with depression.