Isradipine is part of a class of drugs called calcium channel blockers. It helps slow down the rate at which calcium moves into your heart and blood vessel walls. This, in turn, helps to relax the vessels, which allows better blood flow and makes it easier for the heart to pump blood.
There are two basic types of calcium channel blockers: dihydropyridine and non-dihydropyridine. The most important difference between the two is that non-dihydropyridine calcium channel blockers can slow down the heart rate, while dihydropyridine calcium channel blockers do not. Isradipine is a dihydropyridine calcium channel blocker, which means that it does not usually decrease the heart rate.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Dynacirc [package insert]. Liberty Corner, NJ: Reliant Pharmaceuticals;2006 May.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed March 20, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed March 20, 2007.
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