Blood Pressure Home > Hydrochlorothiazide Warnings and Precautions

There are many important hydrochlorothiazide warnings and precautions to be aware of. For example, several possible side effects can occur when taking this drug, such as extremely low blood pressure, allergic reactions, decreased kidney function, and increased cholesterol and triglyceride levels. Do not take hydrochlorothiazide if you are allergic to any components of the medication, are not producing any urine, or are allergic to sulfonamide-derived drugs.

Hydrochlorothiazide: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking hydrochlorothiazide (HCTZ) if you have:
 
  • Liver disease, including cirrhosis
  • Kidney disease or kidney failure
  • Diabetes
  • Systemic lupus erythematosus (lupus or SLE)
  • A personal or family history of angioedema, which is swelling under the skin
  • Gout
  • Pancreatitis
  • High cholesterol
  • Allergies
  • Asthma
  • Fluid or electrolyte problems
  • Parathyroid problems
  • Had a sympathectomy (a specific kind of surgery)
  • Any allergies, including allergies to hydrochlorothiazide, ACE inhibitors, sulfa drugs, foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you:
 
Tell your healthcare provider about all other medicines you may currently be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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