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In animal studies of Calan and pregnancy, the drug was shown to increase the risk of miscarriages and decreased fetal growth. However, animals do not always respond to medicines in the same way that humans do. Therefore, a healthcare provider may still prescribe Calan if he or she believes the benefits to the pregnant woman outweigh the risks to the unborn child.
An Overview of Calan and PregnancyFor people who are pregnant, Calan® (verapamil hydrochloride) may not be safe. This is based on animal studies that looked at the effects of Calan during pregnancy.
Calan and Pregnancy Category CThe U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans, but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Calan was given a pregnancy Category C rating because of potential problems in animal studies. When given to pregnant rabbits, Calan increased the risk of miscarriages and decreased fetal growth.
However, it is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to pregnant women if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.