AZOR contains two medications (amlodipine and olmesartan) and is prescribed for treating high blood pressure. The medication works by slowing down the rate at which calcium moves into your heart and blood vessel walls, and by blocking angiotensin II receptors (which can cause blood vessels to constrict). AZOR comes in tablet form and is typically taken once a day. Possible side effects include swelling, dizziness, and flushing.
(Click AZOR Uses for more information on what this drug is used for, including possible off-label uses.)
Who Makes It?
AZOR is made by Daiichi Sankyo, Inc.
How Does AZOR Work?
Amlodipine (one of the components of AZOR) is part of a class of drugs called calcium channel blockers. It helps to slow down the rate at which calcium moves into your heart and blood vessel walls. This, in turn, helps to relax the blood vessels, which improves blood flow and lowers blood pressure. It also makes it easier for the heart to pump blood.
The other component of AZOR (olmesartan) belongs to a group of medications called angiotensin II receptor blockers (often referred to as "ARBs"). Angiotensin II is a potent vasoconstrictor (which means that it causes blood vessels to narrow, which, in turn, increases blood pressure). Olmesartan works by blocking angiotensin II receptors, preventing angiotensin II from having an effect on the blood vessels. This helps the blood vessels relax, which lowers blood pressure.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
AZOR [package insert]. Parsippany, New Jersey: Daiichi Sankyo, Inc.;2013 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed November 16, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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