Blood Pressure Home > Atacand and Depression

There are a few possible side effects of Atacand, and depression is one of them. However, depression is reported in less than 1 percent of the people taking Atacand and it is difficult to tell whether the depression is caused by the medicine, other factors, or a combination of both. Possible symptoms of depression include insomnia, feelings of hopelessness, and a decrease in energy. Anyone who has a history of depression should consult a healthcare provider before taking Atacand.

Is Depression an Atacand Side Effect?

Atacand® (candesartan cilexetil) is a prescription medication used to treat high blood pressure or congestive heart failure. It is part of a class of medicines called angiotensin II receptor blockers. As with any medication, there are several possible side effects that can occur in people taking Atacand. One of these possible side effects is depression.
Depression is a complaint that is reported rarely (less than 1 percent of cases) in people taking Atacand. This data comes from clinical trials that extensively studied Atacand in thousands of people and documented its side effects. The challenge with Atacand and depression is that given how uncommon depression is reported with Atacand and how common it is within the general population, it is difficult to tell whether the depression is caused by Atacand, other factors, or a combination of both.

Atacand and Depression: What Should You Look For?

Depression is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) has depression. Therefore, knowing the symptoms of depression can be helpful.
Possible depression symptoms may include:
  • A persistent sad, anxious, or "empty" mood
  • Feelings of hopelessness and pessimism
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy, fatigue, and being "slowed down"
  • Difficulty concentrating, remembering, and making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite or weight loss, or overeating and weight gain
  • Thoughts of death or suicide and suicide attempts
  • Restlessness and irritability
  • Persistent physical symptoms that do not respond to treatment, such as headaches, digestive disorders, and chronic pain.
Keep in mind that there are other conditions that can share similar symptoms with depression.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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