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Altace Drug Interactions Explained

The following section explains in detail the possible interactions that may occur when Altace is combined with certain other substances.
Combining Altace with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
Aliskiren and Altace should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.  
Studies suggest that combining ACE inhibitors (such as Altace) with ARBs may increase the risk of various problems (such as kidney damage, high potassium levels, or dangerously low blood pressure) without providing significant benefit. In general, Altace should not be combined with ARB medications.
When taking Altace with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Altace is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dosages of either medicine, start you on a lower dose of Altace, and/or monitor you more closely.
Injectable Gold
Reactions have been reported in people taking Altace who received gold injections. These reactions included symptoms such as facial flushing, nausea, vomiting, and low blood pressure.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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