Lotrel Drug Interactions

Lotrel Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Lotrel is combined with any of the drugs listed above.

 

Taking antacids with Lotrel may decrease the absorption of Lotrel into the body. If you are taking antacids, they should be taken at least two hours before or after taking Lotrel.

 

When taking Lotrel with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Lotrel is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dose of the diuretic, start you on a lower dose of Lotrel, and/or monitor you more closely.

 

Reactions have been reported in people taking Lotrel who received gold injections. These reactions included symptoms such as facial flushing, nausea, vomiting, and low blood pressure.

 

Lotrel may increase the risk of lithium toxicity and may increase the lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently and may need to adjust your lithium dosage.

 

If you have kidney disease or kidney failure, taking both NSAIDs and Lotrel may add to the damage that your kidneys are already experiencing. Also, NSAIDs may decrease the effects of Lotrel on lowering your blood pressure. For your particular situation, talk to your healthcare provider about using NSAIDs and Lotrel together.

 

If you are taking Lotrel along with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium supplements or salt substitutes and Lotrel together.