Lotensin HCT

Lotensin HCT is a drug that is used to help lower high blood pressure in adults. The medication works by relaxing the blood vessels and allowing the kidneys to remove more salt and water from the blood in order to reduce blood volume. Lotensin HCT comes in the form of a tablet that is taken once a day, with or without food. As with any medication, Lotensin HCT can cause potential side effects, such as dizziness, cough, or fatigue.

What Is Lotensin HCT?

Lotensin HCT® (benazepril hydrochloride and hydrochlorothiazide) is a prescription medicine that has been licensed to control high blood pressure (hypertension) in adults. Lotensin HCT has not been approved for use in children. Lotensin HCT is not a cure for high blood pressure.
 
(Click Lotensin HCT Uses for more information on what Lotensin HCT is used for, including possible off-label uses.)
 

Who Makes Lotensin HCT?

Lotensin HCT is manufactured by Novartis Pharmaceuticals.
 

How Does Lotensin HCT Work?

Lotensin HCT is a combination of two medicines -- Lotensin® (benazepril) and hydrochlorothiazide.
 Lotensin is part of a class of drugs called angiotensin-converting enzyme inhibitors, or ACE inhibitors for short. Lotensin helps to block the angiotensin-converting enzyme, which is normally part of a reaction in the body that causes the blood vessels to narrow (constrict). By blocking this enzyme, Lotensin causes blood vessels to relax.
 
Hydrochlorothiazide is a diuretic, which is commonly referred to as a "water pill." It works by increasing the amounts of salt and water the kidneys remove from the blood. This extra salt and water is passed out through the urine. By increasing the amount of water removed from the blood, hydrochlorothiazide causes a decrease in blood volume.
 
Because of the effects of both Lotensin and hydrochlorothiazide, Lotensin HCT can lower blood pressure. Because of its combined effects, Lotensin HCT causes a greater drop in blood pressure than when either medicine is used alone.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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