Lotensin HCT Drug Interactions

Narcotics
When taking Lotensin HCT with a narcotic, your blood pressure may decrease too much. In order to decrease the chances of this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of Lotensin HCT, and/or monitor you more closely.
 
Cholestyramine (Prevalite, Questran, Questran Light, LoCholest)
Cholestyramine can bind to Lotensin HCT in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, Lotensin HCT should be taken at least one hour before, or four to six hours after, cholestyramine has been given.
 
Colestipol (Colestid)
Colestipol can bind to Lotensin HCT in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, Lotensin HCT should be taken at least one hour before, or four to six hours after, colestipol has been given.
 
Corticosteroids
Taking corticosteroids with Lotensin HCT may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking a corticosteroid with Lotensin HCT, your healthcare provider may monitor you more closely and/or adjust your dose of medicine as needed.
 
Norepinephrine
Norepinephrine is a medicine that is used to treat very low blood pressure. Lotensin HCT may affect the ability of norepinephrine to raise blood pressure.
 
Corticotropin
Taking corticotropin with Lotensin HCT may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking corticotropin with Lotensin HCT, your healthcare provider may monitor you more closely and/or adjust your dose as needed.
 
Muscle Relaxants
If you are taking both Lotensin HCT and a muscle relaxant, your body may metabolize the drugs differently than intended and increase the muscle relaxant levels in the blood. In order to decrease the chances of this drug interaction, your healthcare provider may monitor you more closely and/or change the muscle relaxant dose.
 
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