Lotensin HCT Drug Interactions

More Detail About Lotensin HCT Interactions

The following sections explain in detail the potentially negative interactions that can occur when Lotensin HCT is combined with any of the drugs listed above.
 
Diuretics
When taking Lotensin HCT with a diuretic, your blood pressure may decrease too much. This is more likely to occur when Lotensin HCT is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dose of medicine, start you on a lower dose of Lotensin HCT, and/or monitor you more closely.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Lotensin HCT can interact with NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, or are taking a diuretic ("water pill") or are dehydrated, taking NSAIDs and Lotensin HCT together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
  
Potassium Supplements or Salt Substitutes With Potassium
If you are taking Lotensin HCT along with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. For your particular situation, talk to your healthcare provider about using potassium and Lotensin HCT together.
 
Potassium-Sparing Diuretics
If you are taking both Lotensin HCT and a potassium-sparing diuretic, your body may metabolize the drugs differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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