Loniten Warnings and Precautions

Make sure your healthcare provider is aware of any other medical problems you have, such as heart disease, kidney problems, or angina, before beginning treatment with Loniten. This medication can also cause drug interactions, so tell your healthcare provider about any other medications, vitamins, or supplements you are taking. Other precautions and warnings with Loniten apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Loniten® (minoxidil oral) if you have:
  • Pheochromocytoma, a rare tumor of the adrenal gland
  • A rare blood disorder called cryoglobulinemia
  • Heart disease, including congestive heart failure (CHF)
  • A history of a heart attack, especially in the past month
  • Angina (chest pain)
  • Kidney disease, such as kidney failure (renal failure)
  • A history of hemolytic anemia or thrombocytopenia (a low platelet level)
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Loniten

Some warnings and precautions to be aware of prior to taking this blood pressure medicine include the following:
  • Loniten may cause your body to retain water and salt, which can cause edema (water weight gain and swelling) and possibly heart failure. You will likely need to take a diuretic, sometimes called a "water pill," to remove the extra water and salt from your body.
It is a good idea to weigh yourself daily to make sure the diuretic is working to prevent this Loniten side effect. If you rapidly gain five or more pounds, or notice any body swelling, contact your healthcare provider. Your medication dosages may need to be changed.
  • Loniten increases heart rate, which can lead to chest pain (angina). Your healthcare provider will likely recommend that you take a medication to help prevent this side effect (usually a beta blocker). You will also need to regularly check your pulse rate to monitor for this side effect. If your pulse rate increases by 20 beats or more a minute, contact your healthcare provider immediately. Ask your healthcare provider if you are unsure how to take your pulse.
  • There have been reports of swelling of the tissue that surrounds the heart and excess fluid buildup around the heart with Loniten use. Pressure on the heart from the excess fluid can lead to heart failure and even death. People with kidney disease may have an increased risk for this side effect. Contact your healthcare provider immediately if you experience symptoms of these problems, which can include:
    • Difficulty breathing, especially while lying down
    • Chest pain
    • Cough
    • Dizziness
    • Fainting.
  • If you have extremely high blood pressure, you may need to start Loniten while in the hospital so you can be closely monitored and your blood pressure can be lowered at a safe rate. Extremely high blood pressure is a serious problem. If the blood pressure is lowered too quickly, potentially dangerous problems may occur.
  • People with kidney failure or on dialysis should be closely monitored while taking this medication. They may need a lower Loniten dosage.
  • Your healthcare provider may closely monitor your kidneys, heart, and blood electrolytes while you are taking Loniten. When you first start this medication, monitoring may be more frequent, every 1 to 3 months, and become less frequent over time, every 6 to 12 months, as you become stable on the medication.
  • In rare cases, people using Loniten may develop a skin rash, which may lead to life-threatening complications. Contact your healthcare provider immediately if you develop any skin rash. He or she will let you know if you need to stop taking Loniten.
  • Loniten is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy (see Loniten and Pregnancy).
  • This drug passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to beginning treatment (see Loniten and Breastfeeding).
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Loniten Medication Information

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