Lasix Drug Interactions

Ethacrynic Acid (Edecrin)
Lasix should not be combined with ethacrynic acid due to the risk of hearing loss.
 
Laxatives
Prolonged use of laxatives may increase the risk of low blood potassium levels (hypokalemia) in people taking Lasix.
 
Licorice
Combining Lasix with large amounts of licorice may increase the risk of low potassium levels (hypokalemia). However, many "licorice" products contain little or no real licorice. For instance, red licorice does not contain any real licorice, and some black licorice products contain anise flavoring instead of licorice.
  
Lithium (Eskalith, Lithobid)
Taking Lasix with lithium may increase the level of lithium in your blood, increasing your chance of side effects. In general, it is usually not recommended to combine lithium with diuretics, including Lasix. Your healthcare provider may need to monitor your lithium level more closely and/or change your lithium dose if you must take both of these drugs at the same time.
 
Methotrexate
Combining methotrexate with Lasix may increase the toxicity of both medications while decreasing the effectiveness of Lasix. Check with your healthcare provider before taking these medications together.
  
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Lasix with NSAIDs can make Lasix less effective and may increase your risk of side effects. Your healthcare provider may need to increase your Lasix dosage or may suggest an alternative to NSAIDs if this interaction is a concern.
 
Phenytoin
Phenytoin may make furosemide less effective. Check with your healthcare provider before taking these medications together.
  
Salicylates
Combining Lasix with a salicylate can increase the level of the salicylate in your blood, increasing your risk of side effects. Talk with your healthcare provider before taking these medications together.
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Lasix Drug Information

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