Lasix Drug Interactions (Cont.)

Lasix Interactions Explained

 
Aminoglycoside Antibiotics
Lasix should not be combined with aminoglycoside antibiotics unless absolutely necessary. Taking these two medications together can increase the chance of permanent hearing loss.
 
Other Blood Pressure Medicine
When taking Lasix with another high blood pressure medication, your blood pressure may decrease too much. In order to decrease the chances of this Lasix interaction, your healthcare provider may monitor you more closely and/or change the dose of either medicine.
 
Corticosteroids
Taking Lasix with corticosteroids may increase your risk of low potassium levels (hypokalemia). Your healthcare provider should check your potassium levels and may need to take steps to correct your potassium levels.
 
Digoxin (Digitek, Lanoxin)
Lasix should be used carefully in people taking digoxin. Lasix can cause low potassium levels (hypokalemia), which can be especially dangerous for people taking digoxin.
 
Ethacrynic Acid (Edecrin)
Lasix should not be combined with ethacrynic acid due to the risk of hearing loss.
 
Lithium (Eskalith, Lithobid)
Taking Lasix with lithium may increase the level of lithium in your blood, increasing your chance of side effects. In general, it is usually not recommended to combine lithium with diuretics, including Lasix. Your healthcare provider may need to monitor your lithium level more closely and/or change your lithium dose.
 
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Lasix with NSAIDs can make Lasix less effective and may increase your risk of side effects. Your healthcare provider may need to increase your dose of Lasix or may suggest an alternative to NSAIDs.
(Lasix Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;