When people take labetalol, sexual side effects may occur. Sexual problems that have been reported with the medication include impotence, ejaculation failure, and Peyronie's disease. If you are taking labetalol and sexual side effects develop, discuss this with your healthcare provider. He or she may prescribe erectile dysfunction medication or recommend another blood pressure medicine.
Labetalol hydrochloride (sold under the brand name Trandate® and available as a generic) is a prescription medicine used for controlling high blood pressure. As with all medicines, labetalol has possible side effects. Some of these side effects can affect a person's sexual well-being. In the case of labetalol, sexual side effects that have been reported include:
Ejaculation failure.
Impotence. Impotence is usually defined as a total inability to achieve erection, an inconsistent ability to do so, or a tendency to sustain only brief erections. Ultimately, impotence is the repeated inability to get or keep an erection firm enough for sexual intercourse. Impotence is also known as erectile dysfunction (or ED for short).
In clinical studies documenting labetalol side effects, ejaculation failure was reported in up to 5 percent of people. Impotence was reported in up to 4 percent of people taking the medication. With both of these sexual side effects, the likelihood increased with increasing doses. With the normal maintenance dose of 200 mg to 400 mg twice a day, impotence occurred in up to 1 percent of people and ejaculation failure in up to 2 percent of people.
Peyronie's disease was reported in less than 1 percent of patients.