Labetalol Overdose

It is possible to overdose on labetalol. Overdose symptoms associated with taking too much labetalol may include wheezing, difficulty breathing, severe decrease in heart rate, and seizures. Treatment for a labetalol overdose may involve medications or "pumping the stomach"; however, once the labetalol has been absorbed into the body, treatment will likely consist of supportive care to treat symptoms of the overdose.

 

Labetalol Overdose: An Overview

Labetalol hydrochloride (Trandate®) is a prescription medication that is used for lowering blood pressure (hypertension). Just like with other medicines, it is possible to take too much labetalol. Labetalol overdose effects will vary depending on a number of factors, including how much labetalol is taken and whether it is taken with any other medicines, alcohol, and/or drugs.
 
If you happen to overdose on labetalol, seek medical attention immediately.
 

Symptoms of a Labetalol Overdose

When someone overdoses on labetalol, the symptoms can vary. Some examples of labetalol overdose signs and symptoms include:
 

Treatment for a Labetalol Overdose

Treatment for a labetalol overdose will vary.
 If the labetalol overdose was recent, the healthcare provider may administer certain medicines or place a tube into the stomach to "pump the stomach." However, there is no readily available treatment that can remove labetalol quickly once it has been absorbed into the body. Therefore, in these cases, treatment involves supportive care. This type of care consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a labetalol overdose may include:
 
  • Fluids through an intravenous line (IV)
  • Medications to increase blood pressure or heart rate
  • Medications to improve breathing
  • Medicines or placement of a pacemaker for abnormal heart rhythms
  • Close monitoring of the heart and lungs.
     
It is important that you seek medical attention immediately if you believe that you may have overdosed on labetalol.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;