If certain medicines are taken with labetalol, drug interactions may occur. Drug interactions with labetalol may involve medications such as calcium channel blockers and tricyclic antidepressants. Other medications that may potentially cause drug interactions with labetalol include cimetidine, nitroglycerine, and certain diabetes medicines (including insulin and oral diabetes medications).
Labetalol hydrochloride (Trandate®) potentially has a number of other medicines with which it may interact. Some of these labetalol interactions can involve medications such as: