Side Effects of Hydrochlorothiazide

There are a number of possible side effects of hydrochlorothiazide, including low blood pressure, weakness, diarrhea, and increased blood sugar. While most side effects do not require medical attention, you should notify your healthcare provider immediately if you experience any serious side effects such as seizures, unexplained swelling of the head and neck, or difficulty breathing.

 

Hydrochlorothiazide Side Effects: An Overview

As with any medicine, there are possible side effects with hydrochlorothiazide (HCTZ). However, not everyone who takes the medicine will experience side effects. In fact, most people tolerate hydrochlorothiazide well. When side effects do occur, in many cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
 
(The side effects discussed below are not a complete list of side effects reported with hydrochlorothiazide. Your healthcare provider can discuss a more complete list of side effects with you.)
 

Specific Side Effects of Hydrochlorothiazide

Hydrochlorothiazide has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated.
 In these studies, side effects are always documented and compared to side effects that occur in a similar group of people not taking the medicine.
 
Based on these studies, hydrochlorothiazide side effects include:
 
(Side Effects of Hydrochlorothiazide Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;