Hydrochlorothiazide Problems

Although people generally tolerate
 hydrochlorothiazide (HCTZ) well, as with any medication, side effects are possible. In most cases, side effects of the drug are minor and either do not require medical attention or can be treated easily. Some of the reported problems with hydrochlorothiazide include:
 
  • A spinning sensation (vertigo)
  • Diarrhea, nausea, vomiting, and constipation
  • Sensitivity to the sun
  • Muscle spasms
  • Hair loss.
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There are also a number of more serious problems that have been reported with hydrochlorothiazide. This type of drug has been known to cause a decrease in kidney function, especially in people with severe congestive heart failure. Hydrochlorothiazide has also been reported to worsen certain conditions, such as lupus, gout, and diabetes.
 
In order to help minimize these risks, tell your healthcare provider about all other medical conditions you have before starting hydrochlorothiazide.
 
(Click Side Effects of Hydrochlorothiazide and Hydrochlorothiazide Warnings and Precautions for more information about these potential hydrochlorothiazide problems, to learn about other side effects associated with this drug, and to find out who should avoid taking this medication.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD