Hydrochlorothiazide Drug Interactions

When medicines such as cholestyramine or other blood pressure drugs are taken together with hydrochlorothiazide, drug interactions can occur. These interactions may result in certain side effects, such as high blood sugar, extremely low blood pressure, or an electrolyte imbalance. Other medicines that may possibly lead to hydrochlorothiazide drug interactions include oral diabetes medication, barbiturates, muscle relaxants, and nonsteroidal anti-inflammatory drugs.

 

Hydrochlorothiazide Drug Interactions: An Introduction

 Hydrochlorothiazide (HCTZ) can potentially interact with a number of other medicines. Some of these hydrochlorothiazide interactions can include:
 
o Amobarbital (Amytal®)
o Butabarbital (Butisol Sodium®)
o Phenobarbital (Luminal®)
o Pentobarbital (Nembutal®)
o Thiopental (Pentothal®)
(Hydrochlorothiazide Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;