Hydrochlorothiazide Drug Interactions (Cont.)

Hydrochlorothiazide Interactions Explained

 
Insulin
Taking insulin with hydrochlorothiazide may cause high blood sugar (hyperglycemia). For your particular situation, your healthcare provider may monitor you more closely and/or adjust your dose of insulin as needed.
 
Oral Diabetes Medication
Taking an oral diabetes medication with hydrochlorothiazide may increase blood sugar levels. For your particular situation, your healthcare provider may monitor you more closely and/or adjust your dose of diabetes medications as needed.
 
Other Blood Pressure Medicine
When taking hydrochlorothiazide with another high blood pressure medication, your blood pressure may decrease too much. In order to decrease the chances of this hydrochlorothiazide interaction, your healthcare provider may monitor you more closely and/or change the dose of either medicine.
 
Alcohol
When taking hydrochlorothiazide with alcohol, your blood pressure may decrease too much. For your particular situation, make sure to talk with your healthcare provider about drinking alcohol while taking hydrochlorothiazide.
 
Barbiturates
When taking hydrochlorothiazide with a barbiturate, your blood pressure may decrease too much. In order to decrease the chances of this hydrochlorothiazide interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of hydrochlorothiazide, and/or monitor you more closely.
 
Narcotics
When taking hydrochlorothiazide with a narcotic, your blood pressure may decrease too much. In order to decrease the chances of this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of hydrochlorothiazide, and/or monitor you more closely.
(Hydrochlorothiazide Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;