Fosinopril (Cont.)

Effects of Fosinopril

A blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure and the bottom number is the diastolic blood pressure. During clinical studies in people taking fosinopril, systolic blood pressure decreased by 8 to 9 mmHg, on average. Diastolic blood pressure decreased by 6 to 7 mmHg, on average. The higher the dose, the greater the drop in blood pressure tended to be. By lowering blood pressure, fosinopril can decrease the risks associated with long-term high blood pressure (see Effects of High Blood Pressure).
 
For people with congestive heart failure, the effects of the drug on the heart and blood vessels cause a decrease in the symptoms of congestive heart failure, including shortness of breath, fatigue, and swelling, and can help improve tolerance for exercise.
 

When and How Do I Take It?

Some general considerations for when and how to take fosinopril include the following:
 
  • The medication comes in tablet form. It is taken once a day.
     
  • It is best to take fosinopril on an empty stomach at least one hour before a meal. However, it may be taken with food if it upsets your stomach.
     
  • Do not break, chew, or crush the tablets.
     
  • Fosinopril should be taken at the same time each day to maintain an even level in your blood.
     
  • For the medication to work properly, you have to take it as prescribed. Fosinopril will not work if you stop taking it.
     

Dosing Information

The dose of fosinopril your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your age
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As with any medication, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Fosinopril Dosing for more information.)
 
(Fosinopril Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;