Depression and Fosinopril

There are a number of potential side effects for people taking fosinopril, and depression appears to be a rare complaint. According to clinical studies that documented fosinopril side effects, depression was reported in less than 1 percent of people who took the medication. However, it can be difficult to determine whether the depression was caused by the medicine, other factors, or a combination of both.

Is Depression a Fosinopril Side Effect?

There are several possible side effects for people taking fosinopril (available as Monopril® and in generic form as Fosinopril Sodium tablets). Depression appears to be a rare complaint in people taking fosinopril. In clinical studies, depression was reported in less than 1 percent of people who took fosinopril. Given how common depression is in the general population and how rare a complaint it is in people who take fosinopril, it is difficult to say whether the depression is caused by the medicine, specific factors, or a combination of factors.

Fosinopril and Depression: What to Look For

While depression may not be a commonly reported side effect of fosinopril, it is extremely common in society today. In fact, in any given one-year period, 9.5 percent of the population (about 18.8 million American adults) has depression. Therefore, knowing the symptoms of depression can be helpful.
Possible depression symptoms may include:
  • Persistent sad, anxious, or "empty" mood
  • Feelings of hopelessness and pessimism
  • Feelings of guilt, worthlessness, and helplessness
  • Loss of interest or pleasure in hobbies and activities that were once enjoyed, including sex
  • Decreased energy; fatigue; feeling "slowed down"
  • Difficulty concentrating, remembering, and making decisions
  • Insomnia, early-morning awakening, or oversleeping
  • Appetite and/or weight loss, or overeating and weight gain
  • Thoughts of death or suicide; suicide attempts
  • Restlessness and irritability
  • Persistent physical symptoms (such as headaches, digestive disorders, and chronic pain) that do not respond to treatment.
Keep in mind that there are other conditions that can share similar symptoms with depression.
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Fosinopril Sodium

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