Exforge is licensed for treating high blood pressure in adults. The medication helps to control blood pressure by relaxing the blood vessels, which improves blood flow. Although Exforge does not cure high blood pressure, it can decrease the chance of developing health problems associated with long-term high blood pressure (such as a stroke or heart disease). There are currently no universally accepted off-label Exforge uses.
As a combination medication, Exforge was initially approved only as treatment for people who had not responded adequately to just a single blood pressure medication. However, Exforge is now approved to be a first-line medication to treat high blood pressure that is unlikely to respond to just a single medication. For instance, Exforge is a good choice for people with very high blood pressure, since a single medication is not likely to lower blood pressure enough.