Exforge Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Exforge is combined with any of the drugs listed above.
ACE Inhibitors
Combining Exforge with ACE inhibitors can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly
(see Exforge and High Potassium for more information).
Alcohol
Drinking alcohol while taking Exforge can increase your risk of low
blood pressure, especially when sitting or standing up suddenly. Talk to your healthcare provider about combining alcohol with Exforge.
Amiloride (Midamor) or Amiloride-HCTZ (Moduretic)
Exforge may interact with
amiloride. Taking these two medications together increases your risk of high potassium levels (hyperkalemia).
Angiotensin II Receptor Blockers (ARBs)
Combining Exforge with ARBs can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
Digoxin (Digitek, Lanoxin)
Exforge should be used carefully in people taking digoxin. Exforge can cause high potassium levels (hyperkalemia), which can be especially dangerous for people taking digoxin.
Eplerenone (Inspra)
Combining Exforge with eplerenone inhibitors can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Taking Exforge with
NSAIDs can make Exforge less effective and may increase your risk of side effects (including kidney problems). Your healthcare provider may need to increase your dose of Exforge or may suggest an alternative to NSAIDs.