Exforge HCT Interactions

Exforge HCT Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Exforge HCT is combined with any of the drugs listed above.
 
ACE Inhibitors
Combining Exforge HCT with ACE inhibitors can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
 
Alcohol
Drinking alcohol while taking Exforge HCT can increase your risk of low blood pressure, especially when sitting or standing up suddenly. Talk to your healthcare provider about combining alcohol with Exforge HCT.
 
Aliskiren
Combining Exforge HCT with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
 
Aliskiren and Exforge HCT should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate-to-severe kidney problems.  
 
Amiloride or Amiloride-HCTZ
Exforge HCT may interact with amiloride. Taking these two medications together increases your risk of high potassium levels (hyperkalemia).
 
Angiotensin II Receptor Blockers (ARBs)
Exforge HCT contains an ARB medication (valsartan). Combining Exforge HCT with other ARBs can increase your risk of high potassium levels in your blood (hyperkalemia). Your healthcare provider should check your potassium levels regularly.
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