Exforge HCT and Pregnancy

It is generally recommended that pregnant women avoid taking Exforge HCT (amlodipine-valsartan-hydrochlorothiazide). This is mostly due to the valsartan component of the medication, which has been shown to present a risk to the fetus in clinical studies. If you are taking this drug and pregnancy occurs, be sure to let your healthcare provider know.

Can You Take Exforge HCT While Pregnant?

Exforge HCT® (amlodipine-valsartan-hydrochlorothiazide) is a prescription blood pressure medication. It is a combination medication, containing hydrochlorothiazide, amlodipine (Norvasc®), and valsartan (Diovan®).
Exforge HCT is generally considered unsafe for use during pregnancy, mostly due to the valsartan component of the medication. Valsartan belongs to a group of medications known as angiotensin II receptors blocker (also known as ARBs).

Pregnancy Category D

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the potential risks.
A pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child. Exforge HCT was given a Category D rating due to the valsartan component.
The hydrochlorothiazide component of the drug has a Category B rating, meaning it is probably safe for use during pregnancy (see Hydrochlorothiazide and Pregnancy). The amlodipine component has a Category C rating, which falls somewhere between the Category B and Category D ratings, in terms of severity (see Norvasc and Pregnancy for more information).
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Exforge HCT Medication Information

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