Drug Interactions With Eprosartan/HCTZ

When certain medications are combined with eprosartan/HCTZ, there is a possibility for negative drug interactions. Some of these reactions can lead to high potassium levels, low blood pressure, decreased effectiveness, and potentially serious side effects. Alcohol, Celebrex, and lithium are among the substances that can react with eprosartan/HCTZ. To avoid potential complications, you healthcare provider may monitor you more closely and adjust your dosages.

An Overview of Eprosartan/HCTZ Interactions

 Eprosartan/HCTZ (Teveten® HCT) may react with many other medications. Some of the drugs that may lead to interactions with eprosartan/HCTZ include but are not limited to:
 
  • Alcohol
  • Allopurinol (Zyloprim®)
  • Amifostine (Ethyol®)
  • Angiotensin-converting enzyme inhibitors (ACE inhibitors), such as:
 
 
  • Other angiotensin II receptor blockers (ARBs), such as:

 

  
  • Barbiturates, such as:
 
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
 
 
 
  • Calcium supplements or calcium-containing antacids
  • Calcitriol (Rocaltrol®, Calcijex®)
  • Corticosteroids, such as:
 
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
  
 
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
 
  • Potassium-sparing diuretics, such as:
 
 
 
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Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD
 
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