Drug Interactions With Eprosartan/HCTZ

More Detail on Drug Interactions With Eprosartan/HCTZ

The following sections explain in detail the potentially negative reactions that can occur when eprosartan/HCTZ is combined with any of the drugs listed above.
ACE Inhibitors
Combining eprosartan/HCTZ with an ACE inhibitor may increase the risk for certain side effects, such as high blood potassium, kidney problems, or extremely low blood pressure. These medications are sometimes used together with appropriate monitoring.
Drinking alcohol while taking eprosartan/HCTZ may lower your blood pressure to unsafe levels. If you consume alcohol while taking this medication, watch for symptoms of low blood pressure, such as dizziness, lightheadedness, or fainting, especially while standing from a seated position. Contact your healthcare provider if you experience these symptoms.
Combining eprosartan/HCTZ with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required. Aliskiren and eprosartan/HCTZ should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate to severe kidney problems.
Eprosartan/HCTZ may increase the risk for potentially serious allopurinol side effects, especially when allopurinol is first started. If you take eprosartan/HCTZ and need to start taking allopurinol, your healthcare provider may choose to monitor you more closely for side effects in the first five weeks of treatment.
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Eprosartan/HCTZ Drug Information

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